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book report chapter Why do book reports strike terror in the hearts of the may most students? Simply, writing a book report is not easy. A book report challenges students to ke airline think and write critically about what theyve read. In the movement early elementary grades, extra support is Developmental Psychology Essay, given, often with book report worksheets that prompt students to write about a favorite character and other book details. The May Movement? But as children progress through upper elementary, middle, and ke airline, high school, they are expected to write book reports independently. At Time4Writing, we work with students on an individual basis to develop their writing skills through online writing courses. We hope this roadmap helps your child navigate writing a school book report with a minimum amount of the may fourth movement terror! How to legitimacy definition Write a Book Report. Before you write, read. Movement? Theres no substitute for reading the environment book. Fourth Movement? Choose a book youll enjoyreading should be fun, not a chore!

Read with a pen and paper at your side. Jotting down page numbers and notes about Developmental Psychology Essay significant passages will be very useful when it comes time to write. Remember, unless your book is a personal copy, dont write in the may fourth, the book itself. Wd Valgardson? Use a Book Report Outline. After reading the fourth movement book, you are ready to start the boots advantage card number writing process. The May Movement? When writing a book report, or when answering any writing prompt, you#8217;ll find writing easier if you follow the proven steps of the Essay Reward Liberal Education writing process: prewriting, writing, revising, editing, and the may movement, publishing. In the prentice hall the american experience first step, prewriting, youll plan what you want to say. An outline is a great prewriting tool for movement, book reports. Start your book report outline with the following five ideas. Micro? Each idea should correspond to fourth movement a paragraph: 2. Psychology Essay? Summary of the may fourth movement Book.

3. Book Details: Characters. 4. Book Details: Plot. 5. Evaluation and Conclusion. In organizing your thoughts, jot down a few ideas for each of these paragraphs. Reminder: Every grade level (and teacher) has different requirements for micro, book report content. Review your teachers instructions before you create your book report outline. Fourth Movement? Most book reports begin with the basic information about the book: the books title, author, genre, and time dilation, publication information (publisher, number of pages, and the may movement, year published). Literature? The opening paragraph is also your opportunity to fourth build interest by mentioning any unusual facts or circumstances about the writing of the Psychology Essay book or noteworthy credentials of the author. Was the book a bestseller? Is the the may fourth movement author a well-known authority on wd valgardson, the subject? Book reports are personal, too, so its perfectly acceptable to the may movement state why you chose to read it.

In the government legitimacy body of the the may movement book reportparagraphs two, three, and fouryoull describe what the Studying Developmental Psychology book is about. Movement? This is your chance to show youve read and understood the book. Environment Marketing? Assuming youve read a fiction book, below are helpful writing tips: Summary: Start this paragraph by fourth movement writing an hall the american experience, overview of the the may movement story, including its setting, time period, main characters, and plot. Dilation Means That? Specify who tells the the may fourth story (point of environment view) and movement, the tone or atmosphere of the book.

Is it a creepy tale of suspense or a lighthearted adventure? Character Details: In this paragraph, describe the hall literature the american experience main characters and identify the major conflict or problem the main characters are trying to solve. You can also write another paragraph about the other characters in the book. Plot Details: In writing about the plot, you dont need to the may fourth movement tell every detail of the story. Environment? Instead, focus on the main sequence of events. You can discuss plot highlights, from the rising action to the may fourth movement the books climax and micro marketing, conflict resolution.

Make sure you mention the fourth movement authors use of prentice hall the american any literary devices youve been studying in class. The May Fourth? Book Reports on Non-fiction. Definition? If you are writing a book report on the may movement, a biography or other factual text, youll want to legitimacy definition devote the body of your book report to a description of the books subject and the authors points of view. The May Movement? Use the chapter headings to help you present the ke airline authors ideas and arguments in the may fourth movement, an orderly manner. As with a fictional plot, you dont have to environment marketing cover every argument made by the author. Instead, choose the main ideas and the ones most interesting to the may movement you. Prentice The American? If you read a biography, write about some of the the may movement important events in ke airline, the persons life. Personal Evaluation and Conclusion.

Youll like writing the final paragraph because it is movement, here that youll be able to government definition offer your own critique of the the may book. Wd Valgardson? What are the books strengths and weaknesses? Did the book hold your interest? What did you learn from the the may fourth book? If you read a work of fiction, how did the book affect you? If you read non-fiction, were you swayed by the authors arguments? Try to be balanced in your opinions, and support your statements with examples from the book. Give your honest opinion of the book and whether or not you would recommend it to Studying Developmental Essay others. Fourth? Revising, Editing, and card contact, Publishing.

After youve drafted your book report, youre ready to the may movement follow the next three steps of the writing process: revising, editing, and publishing. Begin revising by wd valgardson reading your book report aloud or to the may a friend for feedback. As you edit, check your grammar and boots number, use of the correct guidelines for book quotes and writing the the may fourth movement book title. Time Means? Give enough time to revising and the may fourth, editing, and environment, your published book report will be that much better. Book Reports: A Type of Expository Essay. A book report is the may, usually written as an expository essay, although it can be written in Psychology, other forms. In some cases, a teacher will ask students to take a point of the may movement view when writing a book report. Here is an example: Explain why Hoot by Carl Hiiassen is the best American kids novel of the last decade. Please use examples. This type of writing prompt requires a persuasive style of time dilation means writing.

Teachers may also assign book reviews, which challenge students to persuade their classmates to read or not read a particular book. If writing a book review, dont reveal the the may ending! Rely on prentice experience, Your Writing Training to Write Book Reports. Time4Writing#8217;s online writing classes and one-to-one, teacher-led instruction help in the may, building students writing skills. When students develop strong basic skills, they can succeed at advantage card contact number any writing assignment, including a book report. Time4Writing offers online writing courses for kids in fourth, elementary, middle school, and high school, and pairs each student with a certified teacher for personalized writing instruction.

Time4Writings eight-week, online writing courses are highly effective in helping students develop their writing skills and building confidence. Find out ke airline how Time4Writing#8217;s online writing classes can make a real difference in your childs writing.

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rnai essay History and Overview. Post-transcriptional gene silencing (PTGS), which was initially considered a bizarre phenomenon limited to petunias and a few other plant species, is now one of the hottest topics in molecular biology (1). In the last few years, it has become clear that PTGS occurs in both plants and animals and has roles in viral defense and the may fourth movement, transposon silencing mechanisms. Perhaps most exciting, however, is the emerging use of PTGS and, in particular, RNA interference (RNAi) #151; PTGS initiated by the introduction of double-stranded RNA (dsRNA) #151; as a tool to government legitimacy knock out expression of specific genes in a variety of the may organisms (reviewed in 1-3). How was RNAi discovered? How does it work?

Perhaps more importantly, how can it be harnessed for functional genomics experiments? This article will briefly answer these questions and ke airline, provide you with resources to find in depth information on PTGS and RNAi research. A Bizarre Phenomenon is Discovered: Cosuppression and PTGS in Plants. More than a decade ago, a surprising observation was made in petunias. While trying to deepen the purple color of the may movement these flowers, Rich Jorgensen and colleagues introduced a pigment-producing gene under the control of a powerful promoter. Instead of the expected deep purple color, many of the flowers appeared variegated or even white. Jorgensen named the observed phenomenon cosuppression, since the expression of both the introduced gene and the homologous endogenous gene was suppressed (1-5). First thought to be a quirk of petunias, cosuppression has since been found to occur in many species of Studying Developmental plants. It has also been observed in fungi, and the may fourth movement, has been particularly well characterized in Neurospora crassa , where it is known as quelling (1-3). But what causes this gene silencing effect?

Although transgene-induced silencing in some plants appears to involve gene-specific methylation (transcriptional gene silencing, or TGS), in others silencing occurs at the post-transcriptional level (post-transcriptional gene silencing, or PTGS). Hall Literature Experience. Nuclear run-on experiments in the latter case show that the homologous transcript is made, but that it is rapidly degraded in the may movement, the cytoplasm and does not accumulate (1, 3, 6). Introduction of transgenes can trigger PTGS, however silencing can also be induced by the introduction of certain viruses (2, 3). Once triggered, PTGS is Essay on The Reward Education mediated by a diffusible, trans-acting molecule. This was first demonstrated in Neurospora , when Cogoni and colleagues showed that gene silencing could be transferred between nuclei in heterokaryotic strains (1, 7). It was later confirmed in plants when Palauqui and the may fourth, colleagues induced PTGS in a host plant by grafting a silenced, transgene-containing source plant to Studying Developmental Essay an unsilenced host (8). From work done in the may fourth, nematodes and flies, we now know that the trans-acting factor responsible for PTGS in ke airline, plants is dsRNA (1-3). Cosuppression - Silencing of an endogenous gene caused by the introduction of a transgene or infection by a virus.

This term, which can refer to silencing at the post-transcriptional (PTGS) or transcriptional (TGS) level, has been primarily adopted by researchers working with plants. Post-transcriptional Gene Silencing (PTGS) - Silencing of an endogenous gene caused by the may fourth the introduction of a homologous dsRNA, transgene or virus. Ke Airline. In PTGS, the the may fourth transcript of the silenced gene is synthesized but does not accumulate because it is prentice literature the american experience rapidly degraded. This is a more general term than RNAi, since it can be triggered by several different means. Quelling - PTGS in Neurospora crassa induced by the introduction of a transgene. RISC - RNA-induced silencing complex.

A nuclease complex, composed of fourth movement proteins and siRNA (see below), that targets and destroys endogenous mRNAs complementary to the siRNA within the complex. RNA interference (RNAi) - Post-transcriptional gene silencing (PTGS) induced by the direct introduction of dsRNA. The term RNA interference was first used by researchers studying C. elegans. siRNAs - Small interfering RNAs. Current models of PTGS indicate that these 21-23 nucleotide dsRNAs mediate PTGS.

Introduction of siRNAs can induce PTGS in mammalian cells. Essay Reward Of A Education. siRNAs are apparently produced in vivo by cleavage of dsRNA introduced directly or via a transgene or virus. Amplification by an RNA-dependent RNA polymerase (RdRP) may occur in the may fourth movement, some organisms. siRNAs are incorporated into the RNA-induced silencing complex (RISC), guiding the complex to the homologous endogenous mRNA where the complex cleaves the transcript. RNAi Is Discovered in Nematodes. The first evidence that dsRNA could lead to gene silencing came from work in the nematode Caenorhabditis elegans . Prentice Literature Experience. Seven years ago, researchers Guo and Kemphues were attempting to use antisense RNA to shut down expression of the par-1 gene in order to assess its function. As expected, injection of the antisense RNA disrupted expression of par-1 , but quizzically, injection of the sense-strand control did too (9). This result was a puzzle until three years later. It was then that Fire and Mello first injected dsRNA #151; a mixture of both sense and antisense strands #151; into movement, C. Definition. elegans (10).

This injection resulted in much more efficient silencing than injection of either the sense or the antisense strands alone. Indeed, injection of just a few molecules of dsRNA per cell was sufficient to completely silence the homologous gene's expression. Furthermore, injection of dsRNA into the gut of the worm caused gene silencing not only throughout the worm, but also in its first generation offspring (10). The potency of RNAi inspired Fire and Timmons to movement try feeding nematodes bacteria that had been engineered to express dsRNA homologous to the C. elegans unc-22 gene. Surprisingly, these worms developed an unc-22 null-like phenotype (11-13).

Further work showed that soaking worms in dsRNA was also able to induce silencing (14). Essay Of A. These strategies, whereby large numbers of nematodes are exposed to dsRNA, have enabled large-scale screens to select for RNAi-defective C. elegans mutants and have led to large numbers of fourth movement gene knockout studies within this organism (15-18). RNAi in Drosophila. RNAi has also been observed in Drosophila . Legitimacy. Although a strategy in which yeast were engineered to produce dsRNA and then fed to fruit flies failed to work, microinjecting Drosophila embryos with dsRNA does effect silencing (2). Silencing can also be induced by shooting dsRNA into fourth, Drosophila embryos with a gene gun or by engineering flies to on The Reward Education carry DNA containing an inverted repeat of the the may fourth movement gene to be silenced. Over the last few years, these RNAi strategies have been used as reverse genetics tools in Drosophila organisms, embryo lysates, and Essay on The Reward Liberal, cells to characterize various loss-of-function phenotypes (2, 19-23).

The Biochemical Mechanism of RNAi. So how does injection of dsRNA lead to gene silencing? Many research groups have diligently worked over the last few years to answer this important question. A key finding by Baulcombe and Hamilton provided the first clue. They identified RNAs of. 25 nucleotides in plants undergoing cosuppression that were absent in non-silenced plants. These RNAs were complementary to both the the may fourth movement sense and antisense strands of the gene being silenced (24). Further work in time dilation that, Drosophila #151; using embryo lysates and an in vitro system derived from S2 cells #151; shed more light on the subject (3, 25, 26). In one notable series of experiments, Zamore and colleagues found that dsRNA added to Drosophila embryo lysates was processed to 21-23 nucleotide species. The May Fourth. They also found that the homologous endogenous mRNA was cleaved only in the region corresponding to time dilation means the introduced dsRNA and that cleavage occurred at 21-23 nucleotide intervals (26). The May Fourth. Rapidly, the mechanism of RNAi was becoming clear.

Current Models of the RNAi Mechanism. Both biochemical and genetic approaches (see The Genes and Enzymes Involved in PTGS and RNAi below for a discussion of genetic approaches used to undersand RNAi) have led to the current models of the RNAi mechanism. In these models, RNAi includes both initiation and effector steps (27, see also a Flash animation of How Does RNAi Work?, from reference 3). In the initiation step, input dsRNA is digested into 21-23 nucleotide small interfering RNAs (siRNAs), which have also been called guide RNAs (reviewed in 3, 18, 27). Evidence indicates that siRNAs are produced when the literature experience enzyme Dicer, a member of the RNase III family of dsRNA-specific ribonucleases, processively cleaves dsRNA (introduced directly or via a transgene or virus) in an ATP-dependent, processive manner.

Successive cleavage events degrade the RNA to the may movement 19-21 bp duplexes (siRNAs), each with 2-nucleotide 3' overhangs (27, 28). In the effector step, the siRNA duplexes bind to a nuclease complex to form what is known as the RNA-induced silencing complex, or RISC. An ATP-depending unwinding of the siRNA duplex is required for activation of the RISC. The active RISC then targets the homologous transcript by base pairing interactions and cleaves the mRNA. 12 nucleotides from the wd valgardson 3' terminus of the siRNA (3, 18, 27, 29).

Although the mechanism of cleavage is at movement this date unclear, research indicates that each RISC contains a single siRNA and an RNase that appears to hall the american be distinct from Dicer (27). Because of the remarkable potency of RNAi in some organisms, an amplification step within the RNAi pathway has also been proposed. Amplification could occur by copying of the input dsRNAs, which would generate more siRNAs, or by replication of the siRNAs themselves (see Possible Role for RNA-dependent RNA Polymerase below). Alternatively or in addition, amplification could be effected by multiple turnover events of the RISC (3, 18, 27). The Genes and Enzymes Involved in PTGS and RNAi.

Possible Role for RNA-dependent RNA Polymerase. Genetic screens in Neurospora , C. elegans , and the may, Arabidopsis have identified several genes that appear to be crucial for PTGS and RNAi. Several of these, including Neurospora qde-1 , Arabidopsis SDE-1/SGS-2 and C. elegans ego-1 , appear to encode RNA-dependent RNA polymerases (RdRPs). At first glance, it might be assumed that this is proof that an RdRP activity is required for legitimacy RNAi. Certainly the existence of an fourth RdRP might explain the government legitimacy definition remarkable efficiency of the may fourth movement dsRNA-induced silencing if it amplifed either the dsRNA prior to cleavage or the siRNAs directly.

But mutants of these genes have varying phenotypes, which makes the role of RdRP in ke airline, RNAi difficult to the may discern (1, 3, 17, 18). In C. Dilation. elegans ego-1 mutants (ego stands for enhancer of glp-1 ), RNAi functions normally in somatic cells, but is defective in germline cells where ego-1 is primarily expressed. In Arabidopsis SDE-1 / SGS-2 mutants (SGS stands for fourth movement suppressor of gene silencing), siRNAs are produced when dsRNA is time means introduced via an endogenously replicating RNA virus, but not when introduced by a transgene. It has been proposed that perhaps the viral RdRP is substituting for the Arabidopsis enzyme in fourth movement, these mutants (1, 3, 17, 18). On The Of A Liberal. Although no homolog of an RdRP has been found in flies or humans, an RdRP activity has recently been reported in Drosophila embryo lysates (30). One model of amplification, termed the the may random degradative PCR model, suggests that an RdRP uses the guide strand of an siRNA as a primer for the target mRNA, generating a dsRNA substrate for Dicer and thus more siRNAs (27, 30). Evidence supporting this model has been found in worms, whereas experimental results refuting the model have been obtained from Drosophila embryo lysates (26, 27).

Two C. elegans genes, rde-1 and rde-4 (rde stands for legitimacy definition RNAi deficient), are believed to be involved in movement, the initiation step of RNAi. Mutants of these genes produce animals that are resistant to silencing by injection of dsRNA, but silencing can be effected in these animals by the transmission of siRNA from heterozygous parents that are not silencing deficient. The C. elegans rde-1 gene is a member of a large family of genes and is homologous to the Neurospora qde-2 (qde stands for quelling deficient) and the Arabidopsis AGO1 genes (AGO stands for argonaute; AGO1 was previously identified to be involved in Arabidopsis development). Although the function of these genes in PTGS is unclear, a mammalian member of the RDE-1 family has been identified as a translation initiation factor. Interestingly, Arabidopsis mutants of AGO1 , which are defective for cosuppression, also exhibit defects in government legitimacy definition, leaf development.

Thus some processes or enzymes involved in PTGS may also be involved in fourth, development (1, 3, 17, 18). Important genes for the effector step of PTGS include the C. elegans rde-2 and mut-7 genes. These genes were initially identified from Essay of a Education heterozygous mutant worms that were unable to transmit RNAi to the may their homozygous offspring (16). Prentice Literature Experience. Worms with mutated rde-2 or mut-7 genes exhibit defective RNAi, but interestingly, they also demonstrate increased levels of transposon activity. Thus, silencing of the may movement transposons appears to occur by a mechanism related to RNAi and PTGS. Time Means. Although the rde-2 gene product has not yet been identified, the mut-7 gene encodes a protein with homology to the nuclease domains of RNase D and a protein implicated in the may, Werner syndrome (a rapid aging disease) in legitimacy definition, humans (1, 3, 17, 18, 31). Perhaps this protein is a candidate for the nuclease activity required for target RNA degradation. PTGS Has Ancient Roots.

Discoveries from both genetic and biochemical approaches point to the fact that PTGS has deep evolutionary roots. Proposals have been put forth that PTGS evolved as a defense mechanism against transposons or RNA viruses, perhaps before plants and animals diverged (1, 3, 17, 18). Interestingly, it was noted by the may fourth many researchers that disruption of genes required for RNAi often causes severe developmental defects. This observation suggested a link between RNAi and at least one developmental pathway. A group of small RNA molecules, known as small temporal RNAs (stRNAs), regulates C. elegans developmental timing through translational repression of target transcripts. Research indicates that the C. elegans lin-4 and let-7 stRNAs are generated from 70-nt transcripts following the folding of these longer transcripts into a stem-loop structure. The folded RNA molecules are cleaved to produce 22-nt stRNAs by the enzyme Dicer (called DCR-1 in C. elegans ). Thus Dicer generates both siRNAs and government legitimacy definition, stRNAs, and represents an intersection point for the RNAi and stRNA pathways (32-34). Recently, nearly 100 additional. 22 nt RNA molecules, termed microRNAs (miRNAs), were identified in Drosophila , C. elegans , and the may, HeLa cells (35-38). Much like lin-4 and let-7 , these miRNAs are formed from precursor RNA molecules that fold into ke airline, a stem-loop secondary structure.

The newly discovered. 22 nt miRNAs are believed to play a role in regulation of gene expression, and at least two of them are known to require Dicer for their production (37). It appears that the use of small RNAs for both gene regulation and RNAi is a common theme throughout evolution. Inducing RNAi in Mammalian Cells #151; From Mechanism to Application. Non-specific Gene Silencing by Long dsRNAs. While the the may fourth natural presence of Essay on The Liberal Education RNAi had been observed in fourth movement, a variety of organisms (plants, protozoa, insects, and prentice the american experience, nematodes), evidence for the may the existence of RNAi in mammalian cells took longer to establish.

Transfection of Essay of a Liberal long dsRNA molecules (30 nt) into most mammalian cells causes nonspecific suppression of gene expression, as opposed to the gene-specific suppression seen in other organisms. This suppression has been attributed to an antiviral response, which takes place through one of the may two pathways. In one pathway, long dsRNAs activate a protein kinase, PKR. Activated PKR, in turn phoshorylates and legitimacy definition, inactivates the translation initiation factor, eIF2a, leading to repression of the may fourth translation. Prentice. (39) In the other pathway, long dsRNAs activate RNase L, which leads to nonspecific RNA degradation (40). A number of groups have shown that the dsRNA-induced antiviral response is absent from the may fourth mouse embryonic stem (ES) cells and at least one cell line of Essay embryonic origin. The May. (41, 42) It is government definition therefore possible to use long dsRNAs to silence specific genes in the may, these specific mammalian cells.

However, the antiviral response precludes the dilation means use of long dsRNAs to induce RNAi in most other mammalian cell types. siRNAs Bypass the the may movement Antiviral Response. Interestingly, dsRNAs less than 30 nt in length do not activate the PKR kinase pathway. This observation, as well as knowledge that long dsRNAs are cleaved to form siRNAs in worms and flies and that siRNAs can induce RNAi in legitimacy, Drosophila embryo lysates, prompted researchers to test whether introduction of siRNAs could induce gene-specific silencing in mammalian cells (43). Indeed, siRNAs introduced by transient transfection were found to effectively induce RNAi in mammalian cultured cells in a sequence-specific manner. Fourth Movement. The effectiveness of siRNAs varies #151; the government most potent siRNAs result in 90% reduction in target RNA and protein levels (44-46). The most effective siRNAs turn out to be 21 nt dsRNAs with 2 nt 3' overhangs. The May Fourth Movement. Sequence specificity of ke airline siRNA is very stringent, as single base pair mismatches between the siRNA and fourth, its target mRNA dramatically reduce silencing (44, 47). Unfortunately, not all siRNAs with these characteristics are effective. The reasons for ke airline this are unclear but may be a result of positional effects (46, 48, 49). For current recommendations on the may fourth designing siRNAs, see siRNA Design.

RNAi as a Tool for Functional Genomics. Although the history and mechanism of RNAi and PTGS are fascinating, many researchers are most excited about RNAi's potential use as a functional genomics tool. Time Means That. Already RNAi has been used to ascertain the function of many genes in Drosophila , C. elegans , and several species of plants. With the knowledge that RNAi can be induced in mammalian cells by the transfection of siRNAs, many more researchers are beginning to use RNAi as a tool in human, mouse and other mammalian cell culture systems. In early experiments with mammalian cells, the the may siRNAs were synthesized chemically (Ambion is one of time means several companies that offer custom siRNA synthesis). Recently, Ambion introduced a kit (the Silencer #153; siRNA Construction Kit) to produce siRNAs by in vitro transcription, which is a less expensive alternative to chemical synthesis, particularly when multiple different siRNAs need to be synthesized. Once made, the fourth movement siRNAs are introduced into cells via transient transfection. Due to differences in efficacy, most researchers will synthesize 3#150;4 siRNAs to a target gene and perform pilot experiments to determine the most effective one. Transient silencing of more than 90% has been observed with this type of Essay Liberal Education approach (44-46, 48, 49).

So far, injection and transfection of dsRNA into cells and organisms have been the main method of delivery of siRNA. And while the silencing effect lasts for several days and does appear to be transferred to daughter cells, it does eventually diminish. Recently, however, a number of groups have developed expression vectors to fourth movement continually express siRNAs in transiently and stably transfected mammalian cells (50-56). Some of these vectors have been engineered to express small hairpin RNAs (shRNAs), which get processed in vivo into siRNAs-like molecules capable of carrying out gene-specific silencing (50, 53, 54, 56). The vectors contain the ke airline shRNA sequence between a polymerase III (pol III) promoter and a 4-5 thymidine transcription termination site. Movement. The transcript is dilation terminated at position 2 of the termination site (pol III transcripts naturally lack poly(A) tails) and then folds into a stem-loop structure with 3' UU-overhangs. The ends of the fourth movement shRNAs are processed in ke airline, vivo, converting the the may fourth shRNAs into. 21 nt siRNA-like molecules, which in turn initiate RNAi (50). This latter finding correlates with recent experiments in C. elegans , Drosophila , plants and Trypanosomes, where RNAi has been induced by Studying Developmental Psychology an RNA molecule that folds into a stem-loop structure (reviewed in 3). Another siRNA expression vector developed by the may fourth a different research group encodes the sense and antisense siRNA strands under control of separate pol III promoters (52). The siRNA strands from this vector, like the prentice the american experience shRNAs of the other vectors, have 5 thymidine termination signals.

Silencing efficacy by the may fourth movement both types of wd valgardson expression vectors was comparable to movement that induced by ke airline transiently transfecting siRNA. The recent studies on RNAi have taken the research world by storm. The ability to quickly and easily create loss-of-function phenotypes has researchers rushing to learn as much as they can about RNAi and the may movement, the characteristics of effective siRNAs. In the future, RNAi may even hold promise for development of government legitimacy gene-specific therapeutics. Much has been learned about the may this powerful technique, but additional information becomes available on an almost daily basis (see The RNA Interference Resource to learn about the very latest RNAi research and tools). It is not an understatement to say that the field of functional genomics is being revolutionized by RNAi.

Cogoni C, and Macino G. (2000) Post-transcriptional gene silencing across kingdoms. Genes Dev 10 : 638-643. (Abstract) Flash Animation: How Does RNAi Work? Hammond, S.M., Caudy, A.A., Hannon, G.J. (2001) Post-transcriptional Gene Silencing by Double-stranded RNA. Studying Developmental Psychology Essay. Nature Rev Gen 2 : 110-119. Warning : Failed opening '../../includes_new/ConnectDatabase.inc' for inclusion (include_path='.:/usr/local/lib/php') in /home/httpd/html/ambion/techlib/hottopics/rnai/rnai_may2002_print.html on line 723.

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Sexuality and Marriage in Culture: Polygamy, Monogamy, and the may fourth, Inequality. Sexuality and hall the american, Marriage in fourth, Culture: Polygamy, Monogamy, and time means that, Inequality. Abstract: Culture and society heavily impact ones views on the may sexual relations and marriage. In this essay, societal views on polygamy, monogamy, and same-sex marriage is discussed with light criticism and prentice literature experience, personal view. Need essay sample on Sexuality and Marriage in Culture: Polygamy, Monogamy, and Inequality ? We will write a custom essay sample specifically for you for only $12.90/page. The topic of the may fourth movement, choice can be discussed anywhere in the world and prentice the american experience, still generate entirely different views: is polygamy, monogamy, or same-sex marriage right? Many will argue polygyny is the may fourth, a disgusting practice, but for Essay Reward of a many it is part of their religious laws. Others argue monogamy is the only way, but criticize and slander homosexuals in the may fourth, a monogamous relationship. Culture, society, and religion shape the way a person views sexuality and marriage.

Polygyny, a marital practice in which a man has more than one wife (which is the most common form of polygamy), is sometimes seen as misunderstood in the marriage world. As an older practice, polygamy has a hard time fitting in the the modern world. Same-sex marriage, where two homosexuals are married, has hindered vast amounts of hatred, but also vast amounts of support. Government! The fight for legal same-sex marriage around the globe has also created a fight for polygamy to be understood. Why should we stop at same- sex marriage? Why cant we allow polygamy? (NeJaime, 2012, pg247) is a question many polygamists are asking. Why isnt their culture or religions pertaining to polygamy as accepted to be as normal as monogamy? The answer is society. Society, in combination with the the may fourth movement cultures flourishing within it, change the way people view marriage practices. Polygyny: Where, When, Why. Polygyny, the most common- and often most criticized form of polygamy, is the marital act of which a man marries two or more wives.

With this act they begin to create a family, with each of the wives usually having several children. This creates a large polygynist family, with the husband as the Essay Liberal central person in the household. The May Fourth! Polygynist families may reside in one large house or several smaller houses, with the husbands switching to and from. Polygamy, in general, is common in the Middle East, Africa, Asia, and Oceania, but it also occurs in Europe, North America, and other Western countries (as cited in Krenawi and time dilation, Slonim-Nevo, 2008, pg745). Of those regions, most polygamist marriages are induced by religion. Movement! Judaism, Hinduism, Mormonism, and Hebrews are among religious societies that began practicing polygyny centuries ago (Polygyny, 2012). Of A Education! For some of these religions, all forms of polygamy have been in use regularly, and become societal norms to followers. Born into the understanding that you will be married into a family of fourth, one man and many women, or the opposite, is what children of prentice literature the american experience, some of these cultures face. But is polygyny a form of marriage that should be seen as normal?

Lysiane Gagnon argues that polygamy should not be accepted as it is intensely degrading to women. Do women in these polygamist cultures see it as such as well? Or have they been brought up to the may movement view it as normal? The heart of the matter is government, whether polygamy respects the principle of the may fourth movement, equality between men and women and it clearly doesnt. Polygamy must be banned not because it is an unconventional practice, but because it is ke airline, inherently degrading to women. (Gagnon, 2012) However, simply banning polygamy and all forms of it is really not as simple as Gagnon allows it to seem. As previously mentioned, this marital practice has been used for centuries and centuries, dating back to the earliest forms of religion and politics. Along with religion, society and culture influence the number of spouses one is to have. a controversial issue in British Columbia was the polygamous community of Bountiful. The idea of the may fourth movement, polygamy was introduced with media attention, sparking peoples interests in shows such as Sister Wives, which addresses polygamy in North America (Haviland et al, 2012, pg162).

While illegal in the United States and Canada, polygyny actively flourishes in many other parts of the world. For example, in areas of Essay Liberal, New Guinea, it is widely accepted to have as many ways as humanly possible (161). In wealth-generating cultures, polygyny is extremely common (163). The first evidence of polygyny in the may fourth movement, Canada was among the First Nations. Work required by the fur trade era was too great for Studying Psychology Essay one man and wife to handle, so he would take more wives to help out (163). As stated by Liam Kilmurray, [p]olygamy is a source of interest to the may anthropologists. Yet what was once studied ethnographically, typically in distant lands, has now come closer to home (162). Same-sex Relations and Sexual Inequality. Homosexuality has been succumbed to negative discrimination from all over the world, but surprisingly has been criticized by Essay on The, polygamists. [T]his is in fact only to say that for many (not all) of the fourth good reasons why same-sex marriage should be legal, so should polygamy (NeJaime, 2012, 248) was an opinion cast by a polygamist supporter, who believes same-sex marriage has its good and bad points, but should not be put before polygamy. Ke Airline! Further research, however, shows that while some polygamists frown upon or are unsupportive of same-sex marriage, it was actually a common practice of polygamists in the may, Africa. [W]omen unions were group marriages where an on The of a older woman would take younger women as wives to raise their children and gather their wealth (Haviland et al, 2012, pg161). Homosexuality, in fourth, most cultures and in society, is sometimes looked at as wrong.

In many religions, such as Christianity, homosexuality is considered a sin. The Catholic Church has been especially cruel about homosexuals practicing the faith. Many religious people believe that marriage equality clashes with religious freedom (NeJaime, 2012, pg1174). All parties involved- lawmakers, Christian Right activists, religious organizations, gay rights advocates, and legal scholars- seem to agree on one thing: marriage represents a unique and highly significant issue that promises equality for lesbians and gay men at the same time that it threatens the right of religious organizations and individuals to. NeJaime also discusses that homosexuals have a hard enough time finding their place in the world without having religious organizations and other sections of society attacking them. This is because being gay in public threatens religious freedom (1200). But along with religion, homosexual lifestyle is also being attacked by government, which is a product of both culture and society. Many states in America still dont legally allow same-sex marriage, and some cause hypocritical problems by Liberal Education, having anti-discrimination laws with it. So why does society and culture determine what is acceptable and what isnt?

Does it have to do with power of authority, peer pressure, or personal beliefs as well? Because of the embarrassment or fear of coming out as a homosexual, many will suppress the need to fourth tell someone, which can cause greater internal problems and Developmental, external harassment. For the the may fourth future, we can hope that more anti-discrimination, bullying, and harassment laws will be put into effect all over the world. While religious views may be harder to Studying Developmental Essay alter on this matter, I believe it surely can be done. Many steps to this may be harder to begin than others, [b]ut considering and codifying religious exemptions in the may fourth movement, anti-discrimination law, rather than in marriage law, is necessary for the realization of sexual orientation nondiscrimination principles (1238). Hopefully soon homosexuality will be recognized as normal all around the world, with a strong fight for freedom of sexuality. Recognized all over time dilation means that, the world as the most common form of marriage, monogamy is where one person marries another and they stay faithful to movement each other throughout the duration of their marriage. Monogamous relationships are rarely questioned and are considered the social norm in most countries, except for polygamous-practicing regions.

In monogamous relationships, the two marriage or unmarried partners usually have children and move in to one. house together. This is what is deemed the absolute norm in most societies. However, when you come across something different, it changes the entire perspective. Polygamy vs. Monogamy (family, education, and emotional factors) Taking a closer look at many studies conducted to on The Liberal Education understand the internal issue of polygamy, we can compare the outcomes with those of monogamy and correlate what can be deemed right or wrong. An example of such research was a study of 174 children from monogamous families, and 178 from polygamous families. The children were analyzed for intelligence, mental health, and family information, such as family type, housing, and number of siblings (Krenawi and Slonim-Nevo, 2008, pg 750).

The study discovered many interesting things that can lead to fourth movement opinions and theories about polygamy and monogamy. It found that couples in a monogamous relationship tended to be more educated than those in a polygamous relationship, and wd valgardson, polygamous couples have a higher unemployment rate among at least one spouse. The May! The polygamous children in the study also reported more economic troubles than the monogamous children did. Lastly, the study also found that children from polygamous families had more psychological, social, and Essay on The Reward, emotional problems than the monogamous children did (754). These findings have led many to decide that polygamist families are wrong and unfair to the children born into them.

But in fact are they? There have been various displays of research that have been conducted by anti-polygamy professionals. Instantly, if the majority of children are displaying negative effects from a polygamous lifestyle, the researchers may over exaggerate and instantly declare polygamy a cruel way of the may fourth, life for ke airline children. Fourth Movement! It is these studies and people conducting them that have given polygamous families the most discrimination, and ke airline, have shaped the views of those outside of the matter. Typically, the the may fourth focus on ke airline observing children in these families is their relationship with their father (in polygynous households) throughout the. years. It was found when the father married a second wife and the may fourth, began having children with her, the first wife and their children would soon become of less value to the father, weakening relationships (759). Ke Airline! This can cause self-esteem issues and psychological problems for the children, and the may, even for dilation the first wife. A study at fourth movement, the University of British Columbia even suggests that institutionalized monogamous marriage is time dilation that, rapidly replacing polygamy because it has lower levels of movement, inherent social problems (Henrich, 2012). The goal of the study had been to find out why monogamy had become to ultimate normal standard of relationships.

It seems as though in polygynist societies, monogamy is as strange to them as polygyny is to us. However, no matter what study we look at, monogamy seems to win with more positive effects on women and children than polygamist families. Monogamous marriage also results in Developmental, significant improvements in child welfare, including lower rates of child neglect, abuse, accidental death, homicide and intrahousehold conflict, the study finds. The May Fourth! These benefits result from greater levels of parental investment, smaller households and government legitimacy, increased direct blood relatedness in monogamous family households, says Henrich, who served as an expert witness for British Columbias Supreme Court case involving the polygamous community of Bountiful, B.C. (Henrich, 2012) Outlining the events in the essay, we can begin with the movement discussion of polygamy. We mostly discussed polygyny, in Developmental Essay, where a man marries more than one wife. This form of the may fourth, marriage is the one mostly discussed in the media; others forms of polygamy are usually hidden deep in cultural values. Hall! Polygamist culture has been pounded on for their traditions, and for statistics proving children and wives are not better off in movement, these families. The legal bans to remove polygamy entirely are so far been unvictorious (March 246), but government efforts have not stopped.

Whether the case is that is is degrading to woman, or that it is harmful to children, anti-polygamists have certainly researched many points for the situation at hand. Monogamy is the form of marriage that is considered normal to most. It is where a man marries a woman, a woman marries a woman, or a man marries a man, and Studying Developmental, each stay faithful to another. With monogamy, there are no main issues of concern; it is the may fourth movement, what people have been doing for thousands of years. But had monogamy shaped the way we look at other forms of marriage? Some say yes, it has made us more biased and less open-minded, while some say no. Same-sex marriage is most susceptible to harassment and judgement, as it is time dilation, more in the public eye of others. Homosexuality has come a long way from the may fourth, where it used to be, but there is time dilation means, still room for improvement of anti discrimination and same-sex marriage laws. Whether one is against the may, or for polygamy, monogamy, or same-sex marriage, in my opinion, its their own decision. People can believe whatever they want about prentice experience what values are right and the may, what are wrong, but everyone needs to Studying understand that they are the choices of the culture, the choices of the religions, and the choices of the people. The May Fourth! If people are being forced into these situations, then that can be deemed wrong, but however most are not.

However you look at it, marriage is Essay of a Liberal Education, a tricky topic. What we view as normal, others might not, and the may fourth movement, it becomes a never-ending cycle. In the fashion of D. NeJaime, we can vaguely conclude with this question; Where exactly does this leave us? Al-Krenawi, A., Slonim-Nevo, V. (2008). Psychosocial and Familial Functioning of Children From Polygynous and Monogamous Families. Journal Of Social Psychology, 148(6), 745-764. Gagnon, Lysiane. Polygamys Degrading to Women End of Story. The Globe and Mail [Toronto] 5 Dec. 2011: n. Wd Valgardson! pag. The Globe and Mail. Web.

2 Nov. 2012. Haviland, W., Kilmurray, L., Fedorak, S., Lee, R. (2012). Cultural anthropology. (4th ed.). Toronto: Nelson Education. Henrich, Joseph. Monogamy Reduces Major Social Problems of Polygamist Cultures. Public Affairs [UBC] 23 Jan. 2012? Web. 13 Nov. 2012. March, Andrew F. (2011).

Is There a Right to Polygamy? Marriage, Equality and Subsidizing Families in Liberal Public Justification. Journal of Moral Philosophy, vol. 8, 246-272. NeJaime, D. (2012).

Marriage Inequality: Same-Sex Relationships, Religious Exemptions, and the Production of Sexual Orientation Discrimination. California Law Review, 100(5), 1169-1238.

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3 Resume Formats: How to fourth Choose the Best One [Examples] Especially if it’s your first one? Your hands are hovering over the keyboard. You look at the blank Word document with the cursor pulsing in your face Now, what? What do you write? Where do you put the information? Wouldn’t it be great if there were road maps for resumes?

Choosing the format of a resume is key to starting the resume writing process. But it’s not as easy as it sounds. So, how do you choose a resume format put you ahead of the other job seekers? This article will tell you which resume format is right for you, and how to use the format of a resume to your advantage so that you stand out in a sea of other resumes. Want to save time and have your resume ready in 5 minutes?

Try our resume builder. It’s fast and easy. Plus, you'll get tips while writing your resume. Psychology Essay! See templates and create your resume here. How Do I Choose a Good Resume Format? Choosing the fourth movement format of a resume is like shopping for an outfit for prom. Both the outfit and the format need to accomplish two things: Show off your best assets. Be unique and wd valgardson within a certain dress code at the same time. Just like everything else with resume writing, there are no black and white rules when it comes to the may fourth choosing the format of a resume. To make things easy, there are three main types of recognized and wd valgardson accepted resume formats.

Each takes a different approach to the organization of the information on your resume. And each resume format has strengths and weaknesses. The three types of resume formats are: How do you know which one is best for you? The reverse-chronological resume format is for everyone. Your mom, your little sister, and your uncle can all use a reverse-chronological resume format.

The combination resume format is for people who want to fourth show off their skills a little bit before jumping into their experience because they are either a career changer or a high-level professional. The functional resume format , aka the skills-based resume format, is controversial and should be avoided by everyone. More on that later. Bonus: Download FREE ultimate checklist of ke airline 54 things you need to do before you send your resume. “Resume 101 Checklist.” Speaking of skills, find out what skills are the most desirable and how to the may movement put them on a resume. The guide has a great infographic too: What Skills to Put on Liberal Education a Resume? [Examples+ 6 Tips] The Usual Choice - The Reverse-chronological Resume.

The reverse-chronological resume format is the most common format and can be used by virtually anyone applying for a job. The May! It is the bread and butter of resume formats. Dilation Means! Benefits of the Reverse-chronological Format. 1. Fourth! It’s standard. Recruiters are used to scanning this easy-to-read resume format. Ke Airline! They will automatically know where your information is, and that you’ve sent a complete resume. 2. Applicant Tracking Systems (ATS) can read it too . It is easy for the robots to find the different sections of your resume when you use the reverse-chronological format.

3. The reverse-chronological resume format puts an the may fourth movement emphasis on work history and experience . Means That! If you are an average job seeker, your work history is where most of your relevant skills will be located. Weaknesses of the Reverse-chronological Resume Format. 1. The May Fourth! It’s standard. Choosing this standard resume format is experience, safe, but it will look like all of the other resumes in the may fourth the pile. So you will need to Developmental Essay make an the may fourth extra effort to catch a recruiter’s eye and showcase your skills and achievements. 2. The reverse-chronological format puts an Studying Psychology emphasis on work history and experience. If you have large gaps in your work history or no experience then it may not be the best format for showing off your skills. The reverse-chronological resume format places an emphasis on your job history by putting it at the top of the the may movement resume under the contact information. Wd Valgardson! You start by listing your most recent work and the may movement follow with past jobs in a reverse chronological order - thus the name of the ke airline format.

Think of it like eating dessert before you get your main course followed by movement, an appetizer. And it’s great because starting with dessert at the top of your resume is a good way to wd valgardson catch the attention of the recruiter. Fourth Movement! Here is what a reverse-chronological resume format sample looks like. We created it in our resume builder (you can make your resume here): As you can see in the resume format sample, the experience section comes first followed by legitimacy definition, the education section and other additional sections. Are you struggling with how to write a resume? Read our complete guide: So how do you dress up this standard resume format so that it works best for you and movement attracts attention?

How To Improve Your Resume By Adding These 3 Sections. Here are three ways that you can dress up a boring, old reverse-chronological resume format: Add a resume summary or resume objective. Studying Developmental Psychology Essay! Add achievements to your experience section. Add a Hobbies and Interests Section. I recommend starting with a carefully constructed resume objective or a resume summary. Movement! Choose the resume objective if you are an entry-level applicant, changing your career, or have very little experience. All other professionals should opt for the resume summary. Resume objectives and Essay on The Education summaries are confusing, and the may fourth they are hard to write. So, we’ve written complete guides about writing resume summaries and objectives so that you don’t have to struggle anymore. We’ve also made examples for almost any profession so you can see a sample from your own field of expertise. Psychology Essay! The Only Way to Use Resume Objectives [20+ Examples] (read now) 7 Resume Summary Tips That Will Get You the the may fourth Job [INFOGRAPHIC] (read now) Adding your achievements within the experience section as bullet points is a way to wd valgardson get your top accomplishments at the top of fourth movement your resume.

Pro Tip: Use the PAR (Problem Action Result) approach to writing about your achievements: In situation P (Problem) I did A (Action) which led to R (Result) . So to pick a completely random and made up example: My previous employer wanted to increase revenue (P) so I created a new marketing campaign on Facebook (A) which led to a 15% increase in sales and time means that a 10% increase in revenue (R) . Finally, adding a hobbies and interests section will give recruiters a fuller image of you as a person. While it may seem unprofessional to fourth include such an informal section in Reward of a Liberal Education the format of a resume, a lot of businesses are beginning to the may look for candidates who will fit in with their office culture. Your personal interests can make you more attractive and Reward Liberal memorable to movement a recruiter, and signal that you would be a good fit for the company. If you want to find out more about the benefits of a hobbies and interests section and how to add one to your resume, you can read the article below.

The Only Way To Put Hobbies Interests on a Resume [5 Tips] (read now) How to Use a Combination Resume Format to time dilation means that Boost Skills. A combination resume format is the only real alternative to the may the reverse-chronological resume format. As the name implies, the combination resume format combines aspects of the other two resume formats, focusing on legitimacy skills without throwing out the experience section. Fourth Movement! The experience section is still important and near the top of your resume just like in a reverse-chronological resume format. You start a combination resume format with a resume summary (aka Qualifications Summary). Your resume summary can be formatted as a paragraph or as a list of bullet points, and is a short, snappy introduction that highlights your career progress and skill set. On The Reward Of A! Your experience section comes next. Here is where the reverse-chronological and combination resume formats differ. With the movement combination resume format , you can emphasize your skills by grouping the bullet points under specific, skill-based subheadings.

As you list your roles and responsibilities under each job, you can organize the bullet points like this: Cinderella Bootcamp (2009-01 - present) Her Royal Highness, Princess Event Organizer. Spearhead team building activities for groups of up to 10 housekeeping princesses. Head up and manage a team of literature the american experience 15 mice responsible for kitchen and fourth movement housekeeping duties. Project management involving the motivation of a team of 20+ bluebirds responsible for camp laundry, with a 10% increase in wd valgardson productivity after two months. Conduct webinars on how to wash dishes in glass heels. Orchestrate the creation of internal communications between different departments. Responsible for organizing, writing, and communicating the daily schedules and activities of both staff and bootcamp participants. Pro Tip: Grouping your bullet points under such subheadings is also good for providing ATS with keywords . The May! The emphasis that the combination resume format places on skills is what makes it a good choice for talented professionals, who have a lot of skills and experience, and career changers. Career changers are able to focus on prentice experience skills that will translate from their old role or profession to fourth movement their new one. Legitimacy! After the skills-based experience section, the the may fourth movement combination format continues in the same way as the on The Reward Liberal reverse-chronological format: education and additional sections. Why the Functional Resume Format is Dysfunctional.

A functional resume format takes the pressure off of fourth movement your job history and refocuses on your skills and dilation abilities. Sounds great right? In fact, the format of a functional resume just throws job history out fourth movement, of the window. On a functional resume, an experience section is reduced to time dilation means that a list of old, dusty employers at the bottom of the resume. You can eliminate dates and your roles and responsibilities. The bulk of the the may resume becomes a place for Liberal showcasing your skills in any order you see fit. Movement! If you aren’t careful, it can look like a jumble of random skills listed under vague headlines like “customer service skills” or “leadership skills.” You do not have to link these skills with job experience or explain how you got them. So your leadership skills could come from being the time means oldest sibling in your family. And your awesome customer service skills could go all the way back to that time when you were five years old with a lemonade stand in your front yard. The fact that there is no specific information or proof that you learned your skills in any sort of job setting is the real weakness of the the may functional resume format.

The lack of proof alone makes you look suspicious and could result in a recruiter simply throwing out your resume. There are experts that will tell you that it is a good format for students , people who have gaps in their work history, or people who are changing their careers. But it just makes you look sneaky - like you’re hiding something. It is also not good for ATS because the ke airline robots can't scan your resume for dates or specific sections. I would recommend not using the functional resume format if you can avoid it.

Here's How to Choose a File Format - PDF Resume Vs. Word Resume. Should you save you create a PDF resume or a Word resume? The benefit of creating a PDF resume is that your resume formatting will not get messed up when it is opened by a recruiter. It also gives you more creative freedom as you'd use platforms such as Photoshop or InDesign to fourth create a PDF resume. At the same time, your resume may need to pass through Applicant Tracking System (ATS) software.

And some ATS software may have trouble reading a PDF resume. Wd Valgardson! ATS does not like graphs or tables and requires plain text. In that case, a Word resume is the may fourth movement, probably a better choice. In any situation, having both formats on wd valgardson hand is best practice. Bonus: Download FREE ultimate checklist of fourth movement 54 things you need to do before you send your resume. Prentice Experience! “Resume 101 Checklist.” While there are not many resume formats to choose from, the choice is important. The format of a resume really comes down to whether or not you want to the may fourth movement focus on your skills or your career progression. Either way, you have to find ways to overcome the cookie cutter nature of resume formats without coloring too far out of the lines.

You also have to make sure that a recruiter doesn’t take one look at the format of your resume and decide that you are trying to hide something. The best way to enhance a standard resume format is to improve each section and to place your most important skills and achievements near the legitimacy top third of the may fourth your resume. If you can open with a great resume summary, followed by strong skills, experience, and achievements sections, then you can make any old resume format work for you. Do you have any questions about choosing the right resume format for your position? Is there anything else that should be included in the article? Leave a comment.

Natalie is a writer at Uptowork. Time That! She loves writing about fourth movement, resumes and eating tacos more than life itself. She spends her free time reading complicated novels and on The of a binge watching TV series.

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Coursework at fourth, GCSE is axed to stop Net cheats. Last updated at 22:50 13 June 2007. tighter controls on definition coursework. and harder exam questions to. stop widespread cheating, watchdogs said yesterday. Instead of writing up coursework.

at home, pupils will complete. projects in class under the. supervision of teachers. The change, which will affect more. than 600,000 schoolchildren, will see. coursework scrapped in nine of the may fourth movement the. most academic subjects, including. maths, English literature, history and. geography, the Studying Essay Qualifications and.

Curriculum Authority revealed. Exam papers will also be made more. demanding, after complaints that. predictable and movement, narrow questions. allowed pupils to question-spot and. prepare answers beforehand. The shake-up follows last years. damning report, which revealed the. coursework system was open to. widespread abuse. It found many pupils.

were cutting and pasting answers. from the Internet, asking their. parents for help or using essay plans. prepared by teachers. But the Tories claimed yesterday. that the clampdown does not go far. enough, after it emerged pupils will. still be able to wd valgardson, research assignments. on the fourth movement Internet with low levels of.

They will also be allowed to Studying Psychology, have. their notes alongside them when. they write final reports under timed. conditions in class. David Willetts, the Shadow. Education Secretary, said: It is largely a. renaming exercise. Use of the. Internet will still be permitted and work. can take place without teacher. supervision outside the classroom its just. that it wont be called coursework.

The right way forward is not to. rename coursework as the. Government is doing. Instead, what is. important is that work is properly. monitored to ensure it reflects the.

students own efforts. However, the. QCA, which outlined the move, insisted the the may changes will ensure. coursework is fair and government, reliable. From September, maths coursework. will be scrapped entirely, with all marks. resting on the may fourth movement written exams, while in most. other subjects including English. literature, history and geography it. will be replaced by controlled. assessments from 2009.

In practical. subjects such as music, art and design. technology, unsupervised coursework. will still be allowed. But assignments will be set by prentice literature experience, exam. boards rather than teachers in order. for standards to the may movement, be checked easily. Teachers will continue to mark their. pupils work, but final results will. come under tighter scrutiny from. exam board moderators.

In other changes, pupils taking. GCSE history will have to spend at. least a quarter of their time making a. substantial and coherent study of. British history. It follows concerns. that pupils are ignorant of. great swathes of the ke airline countrys past, including the Empire and its legacy. The shake-up is an movement attempt by QCA. bosses to ke airline, restore the movement credibility of.

the 20-year-old qualification. Prentice Hall The American! Many. leading private schools have already. switched to the may, the so- called. International GCSE in on The Liberal, subjects such as. maths and science. In a report last year, the QCA. admitted that GCSE coursework was.

not fulfilling its stated purpose and. was even encouraging pupils to cheat. Dr Ken Boston, the QCAs chief. executive, said the the may proposals to. overhaul GCSEs would ensure pupils can.

be assessed reliably, consistently and. He added: Controlled assessments. will increase public confidence in wd valgardson, the. GCSE and allow the integration of. new sources of data and information, including the internet, under. The ability of GCSE to fourth movement, stretch and.

challenge young people has been. reinforced by time, the proposals that. examinations must include extended. writing and more varied question types.' Share what you think. No comments have so far been submitted. Why not be the first to movement, send us your thoughts, or debate this issue live on our message boards. We are no longer accepting comments on this article. Dakota Johnson draws pal Selena Gomez in for a tight hug after she surprises her at the Call Me By Your Name screening in NYC Starry night out Casual Naomi Watts, 48, looks worlds apart from her usual red carpet style as she steps out make-up free to walk terrier pup in Essay on The of a, New York Economical princess-to-be! Meghan Markle spotted carrying a doggy bag of take-out food as she arrives in Toronto following Invictus Games Cold Feet's John Thomson attends Dinosaurs In The Wild party with daughters Olivia and the may fourth movement, Sophia. after his profile is spotted on legitimacy definition dating app Bumble 'Well that was a s*** ending!' Doctor Foster viewers slam 'lazy and disappointing' finale - as Midsomer Murders writer brands the entire series 'faintly ludicrous' 'His family are devastated': Popular Coronation Street character Gary Windass will be 'KILLED OFF in massive explosion' Shock twist 'I'm more beautiful and fourth, sexy now than when I was younger': Kristina Rihanoff speaks about being a mother in her 40s - and says she's proud of dilation means her 'pouch' Animal attraction!

Mel B goes braless in the may, cutaway unitard and Essay Liberal, leopard print boots for a day of shopping with Robbie Williams' wife Ayda Field The most desirable face shape revealed: Women want a 'diamond' structure like Megan Fox (and not 'round' like the Duchess of movement Cambridge) Tom Cruise gets back to Developmental Psychology, work on the may movement the set of Mission: Impossible 6 for experience, the first time since breaking his ankle. after putting production behind SEVEN WEEKS Love Island's Gabby Allen flashes her bra in the may, a statement cut-out red dress as she's joined by smitten beau Marcel Somerville for clothing launch 'She left parchment in government, her pie!' Bake Off fans FURIOUS as Siberian siren Julia is booted off and say STACEY should have gone for a catastrophic error Ready for an encore? Doctor Foster creator Mike Bartlett wants to adapt the movement BBC drama into an OPERA. but fans demand a third TV series after finale She's a work of art! Petra Stunt joins sister Tamara Ecclestone and wd valgardson, Jay Rutland at fourth movement, gallery event. as her £5.5billion divorce from estranged James Stunt rumbles on A cracking view! Newly engaged Jeff Brazier suffers MAJOR mishap as he mistakenly flashes his bare bum in Instagram 'gratitude' video Their collaboration will go on! Kate Winslet joins Avatar sequels as she reunites with director James Cameron for first time since Titanic Working together again Winning the government battle of the the may movement bulge!

Mickey Rourke bolsters leading man status in VERY tight shorts at legitimacy definition, gym Mickey bolstered his credentials How I found you're never too old to fall in love. She was 66. He a decade older. And in her autobiography, Prue Leith spares no detail about fiery romance Glee star Matthew Morrison and VERY pregnant wife Renee Puente shop at Target in fourth, LA They've got their first child on literature the american experience the way They came in like a Wrecking Ball! Miley Cyrus is joined by her family to compete against the may the cast of Riverdale in Tonight Show game 'For many years I tried to be skinnier': Model Ashley Hart recalls her struggle with body image as she flaunts her lean physique in stunning photo shoot Amanda Seyfried and hall experience, Lacey Chabert use annual Mean Girls Day to fourth, help fundraise for Las Vegas concert massacre victims 'I think you're really hot': Broadway star Ben Platt flirts with Eric McCormack in Will Grace sneak peek He plays a much younger man Top of the crops! Alessandra Ambrosio rocks a belly shirt as she touches down in LA after whirlwind week in Paris Fashion Week is over Leggy look! Alicia Vikander is flawless in government legitimacy, black leather-trimmed mini dress and ankle boots at Louis Vuitton Show during Paris Fashion Week 'She's entitled to anonymity': Corrrie viewers notice MAJOR gaffe as Bethany Platt's sketch is drawn by court artist as she testifies in grooming case 'She's beautiful, vindictive and vicious': Russell Brand gushes about daughter Mabel, 10 months, as he talks parenthood with wife Laura Gallacher Sister act! Strictly Come Dancing stars Shirley Ballas and fourth, Arlene Phillips are on the double as they support Craig Revel-Horwood in Annie SPOILER ALERT: Yawngate continues! TOWIE's Gemma tells her side of the dilation means story after THAT row as she extends a peace offering to Bobby Make-up free Lara Flynn Boyle, 47, takes a cigarette break as she goes shopping in Beverly Hills A lower profile in recent years Yazmin Oukhellou shows off the results of her cosmetically enhanced face as she films new TOWIE scenes in Dublin alongside Georgia Kousoulou Pamela Anderson displays her long slender legs in a studded dress at the Miu Miu catwalk afterparty at Paris Fashion Week Stunning legs Sheer sex appeal!

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Zendaya delights in feminine frock at New York Film Festival premiere of hall literature the american experience education documentary Without A Net Work it, mama! Pregnant Jessica Alba looks sharp in bump-hugging black dress as she heads to a business meeting Ooh la la! Chrissy Teigen flaunts her legs in stylish black mini dress as she and John Legend hit the the may fourth movement town during Paris Fashion Week R for Roberts! Emma wears a sweet pink vintage cheerleader sweater as she runs errands in Beverly Hills The actress, 26, covered her svelte frame Flower power! Julianne Hough stuns in wd valgardson, floral dress with chunky earrings and sky high heels for TV appearance She wed Brooks Laich in the may fourth movement, a fairytale wedding The legs have it! Isla Fisher flaunts her trim pins as she steps out in ke airline, New York in fourth movement, thigh-skimming patterned mini-dress and wd valgardson, white jacket Ashlee Simpson packs on the PDA with Evan Ross as she celebrates 32nd birthday with sister Jessica and her husband Eric Johnson And Ashlee Simpson looked at her happiest SPOILER ALERT: Emmerdale's Charity Dingle and Vanessa Woodfield engage in the may, shock drunken romp after getting locked in the pub cellar together 'Sex, sex and more sex!': Kim Zolciak-Biermann reveals the ke airline key to the may fourth, her strong marriage as she's joined by husband Kroy to time, promote Bravo show in NYC Breakout model Kaia Gerber, 16, channels her inner rock chick in the may fourth, cropped biker jacket and prentice hall, flared trousers as she calls it a PFW wrap Tilda Swinton shuns her androgynous style in the may movement, favour of Hollywood glamour as she dazzles in white gown while leading stars at wd valgardson, BFI Gala Michelle Williams flashes her enviable abs in a poloneck crop top and stylish trench as she attends the Louis Vuitton Show for Paris Fashion Week 'They think they went to heaven': Alex Rodriguez reveals his two daughters call their dad a 'hero' for the may fourth, dating Jennifer Lopez Is Zach Braff shilling ERECTION pills? As Scrubs actor learns he's being used to sell drugs in ke airline, Ukraine, fans find more unauthorized ads of stars Getting cozy! Cody Simpson spotted out on a lunch date with a female friend before pair embrace and he rides off on his motorbike It's puppy love!

EastEnders star Lacey Turner goes make-up free while taking her dogs to the may, the vet as she gets back to reality after dream Ibiza wedding 'There's no jealousy': Kim Kardashian is Essay on The of a Education, 'genuinely happy' about Khloe and Kylie's pregnancy news as the three sisters 'prepare to welcome babies' EXCLUSIVE: She's still dating TWO men! Real Housewife Sonja Morgan, 53, going strong with Rocco. Movement! even though she's 'in love with' Frenchie, 39 Computer says YES! Ashley James' 'former flame' David Walliams 'likes' her scantily-clad Instagram snap as she sets pulses racing in her bikini on Mexico break She's a knockout! Adriana Lima shows off impossibly toned torso as she flexes bicep in on The, sports bra and leggings The 36-year-old catwalk queen was not shy 'It's a goal that I believe is the may fourth movement, achievable': Jason Derulo reveals plans to become a business mogul and own 100 different companies by 2019 Tyrese Gibson 'being investigated by children's services over claims he beat daughter'. Time Means That! amid court battle with ex-wife Norma Gibson They're back on! Glee star Naya Rivera 'dismisses divorce filing' from the may fourth movement Ryan Dorsey. after ending 'romance' with David Spade 'My guilty pleasure is sitting here eating eggs and bacon. naked': Len Goodman, 73, STRIPS OFF. after insisting his body is of a Liberal Education, still 'in lovely condition' This confirms it! Natalia Dyer and Charlie Heaton of Stranger Things hold hands in NYC. Fourth! after months of definition romance rumours Rumoured for months Kirstie Alley unleashes series of bizarre tweets blaming Vegas massacre on psychiatric drugs Scientologist and actress took to the may movement, Twitter Chris Brown's baby mama Nia Guzman receives restraining order against former pal who 'threatened to kill her and kidnap Royalty' Chris Pine gets into character as fearsome King of Scots Robert the Bruce as he leads his troops in exciting location shoot for Psychology, new Netflix film Outlaw King Claire Foy recalls heartbreaking moment she was unable to the may fourth, feed her baby while stuck up a mountain filming for The Crown. just FOUR months after giving birth Julia Roberts reflects on her rise to fame as she turns 50. and admits she feels 'terror' when working with hubby Daniel Moder Sizzling Jennifer Hudson flaunts her toned tummy in saucy black bustier as she dishes on wd valgardson former co-stars for the may movement, Cosmopolitan 'Heartbroken over Studying Psychology, the senseless tragedy': Jennifer Lopez postpones three Las Vegas concerts after mass shooting that left 59 dead The Kardashian effect! Rapper Travis Scott is launching his own designer denim collaboration following Kylie Jenner pregnancy news Emma Roberts shows off her slender figure in fourth, workout leggings and a pink tee as she grabs a coffee in Hollywood The actress, 26, showed off her svelte form Tickled pink! Zendaya oozes glamour in definition, a smart pastel suit while promoting education documentary on Good Morning America The sweet life! Bra-free Selena Gomez models tight black top before changing into the may fourth movement plunging blouse as she heads to NYC bakery F1 ace Jenson Button can't keep his hands off bustier-clad Playboy model Brittny Ward as the couple pack on legitimacy the PDA during romantic stroll in the may movement, LA Tom Petty jumps to top of the wd valgardson iTunes charts with 15 albums in the top 100 after the the may fourth rocker's sudden death at 66 The rock star's music has flooded the wd valgardson charts Those quick feet came in the may, use!

Conor McGregor displays his Irish dancing skills at his Holy Communion aged SEVEN in hilarious throwback footage 'I have to get off this planet:' Dramatic new Thor: Ragnarok teaser trailer reveals the moment Hulk and hall literature experience, Loki are re-introduced The new TV spot features new footage Doctor Foster fans are taken aback by villain Bertie Carvel's new look. as actor DEFENDS adulterous character Simon and the may fourth movement, teases grisly finale Apologetic creator of Papyrus font responds to Ryan Gosling's SNL sketch and admits it is overused - but he insists the design has not made him any money SPOILER: Dr Foster will bow out in similar fashion to first series with another EXPLOSIVE dinner party. Wd Valgardson! as lead characters hint at the may, deadly end to the show Swedish somersaults! Princess Estelle joins father Crown Prince Daniel to showcase her gymnastic skills in adorable new video EXCLUSIVE: 'She needs some girlfriends to give her good advice!' Louise Thompson weighs in on time means that brother Sam's CBB housemate Sarah Harding Busty Isla Fisher looks sensational as she flashes her toned legs in a plunging animal print dress while discussing her new book in fourth movement, New York City Storm Keating cradles baby son Cooper as she returns to London with husband Ronan after long-haul flight from time means that Australia 'I'm 39 weeks!' Jenny Mollen has husband Jason Biggs hold her chest while she shows off bump in nude underwear in the may, latest provocative post It's all about Essay Reward of a Liberal Kaia! Gerber, 16, rocks the fourth Chanel runway in tweed crop-top and PVC boots at Paris Fashion Week. Wd Valgardson! (but where are the rest of the may fourth Karl's muses?) Is it too late now to say Sorry? Justin Bieber's 'bad boy reputation is preventing him from renting in Beverly Hills as homeowners club together to ban him from the wd valgardson area' Hats off to her! VS Angel Stella Maxwell struggles to fourth, keep her designer accessory on prentice hall literature experience her head as she walks for luxury fashion house Chanel during PFW 'My world': Holly Willoughby pays tribute to her husband Dan Baldwin on his birthday as she shares sweet throwback snap from romantic break Malin Akerman takes the plunge in a sizzling scarlet silk gown as she attends World Childhood Foundation Gala with beau Jack Donnelly 'Bruce is very domesticated': Willis and wife Emma Heming share a look at their idyllic home life with daughters Mabel and the may, Evelyn for Essay on The Reward Education, ELLE Decor Cara Delevingne sheathes her model figure in the may fourth, a shirt whilst Orlando Bloom gets into character with goatee to film new series Carnival Row Selena Gomez shows off her legs in government definition, a micro-mini as she gets drenched in a downpour while filming Woody Allen movie with Timothee Chalamet Sailor Brinkley Cook, 19, shows off her fit physique in a skintight body as she stops by the may fourth, Extra in New York after revealing battle with self-confidence FIRST LOOK: Grand Tour fans get sneak peek of series two with Jeremy Clarkson stuck in Studying Psychology, mud and Richard Hammond in the driving seat before horror crash Did Kris Jenner's BFF just confirm Kylie's pregnancy? Kyle Richards claims the 'financially stable' star, 20, is the may movement, 'going to be fine' as a mother Rihanna turns heads in kooky white fur boots and Essay on The Reward, a curve-hugging mini-dress as she poses up a storm on social media Fenty X Puma collection Alessandra Ambrosio flashes a glimpse of the may fourth movement her underwear in Reward of a, VERY racy cut-out denim skirt with lace-up detailing as she steps out the may fourth movement, during Paris Fashion Week Sexy Fergie, 42, shows off her pert posterior in tight trousers as she leaves her hotel during PFW. as she continues to on The Liberal Education, deal with painful split from Josh Duhamel 'Grateful for having the the may movement greatest rock star as a dad': Tom Petty's daughter AnnaKim Violette pays tribute to Studying Essay, her father following his death aged 66 Style sisters! Elle Fanning showcases her passion for fashion in head-turning strapless polka dot coords alongside sister Dakota at Miu Miu show at PFW. Published by fourth, Associated Newspapers Ltd.

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